Recombinant Human G6PD Protein, DYKDDDDK-tagged

• Cat.No.: G6PD-445H
• Product Overview: Recombinant protein from the full-length sequence of homo sapiens glucose-6-phosphate dehydrogenase (G6PD), transcript variant 1 (NM_000402), with a DYKDDDDK tag was expressed in human cells.

Specification

• Description: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
• Source: Human Cells
• Species: Human
• Tag: DYKDDDDK
• Molecular Mass: 62.3 kDa
• Endotoxin: < 0.1 ng/μg of protein (<1EU /μg)
• Purity: > 90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Gene Information

• Gene Name: G6PD glucose-6-phosphate dehydrogenase [ Homo sapiens (human) ]
• Official Symbol: G6PD
• Synonyms: G6PD; glucose-6-phosphate dehydrogenase; G6PD1; glucose-6-phosphate 1-dehydrogenase; epididymis secretory sperm binding protein; EC 1.1.1.49
• Gene ID: 2539
• mRNA Refseq: NM_000402
• Protein Refseq: NP_000393
• MIM: 305900
• UniProt ID: P11413