"TNFSF9" Related Products

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Recombinant Human TNFSF9, His-tagged

Cat. No. : TNFSF9-131H
Product Overview : Recombinant human 4-1BB ligand, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography, 23.8 kDa (222aa).
Description : 4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily.4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease.
Sequences of amino acids : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTG GLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRL GVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPAGLPSPR SE
Purity : > 95% by SDS - PAGE
Form : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol
Concentration : 1 mg/ml (determined by Bradford assay)
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 [ Homo sapiens ]
Synonyms : TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; CD137L; 4-1BB-L; TNFSF9;tumor necrosis factor (ligand) superfamily, member 9;receptor 4-1BB ligand; homolog of mouse 4-1BB-L; 4-1BBL; 4-1BB ligand; receptor 4-1BB ligand.
Gene ID : 8744
mRNA Refseq : NM_003811
Protein Refseq : NP_003802
MIM : 606182
UniProt ID : P41273
Chromosome Location : 19p13.3
Pathway : Cytokine-cytokine receptor interaction
Function : cytokine activity; tumor necrosis factor receptor binding

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