|Cat. No. :
|Product Overview :
||Recombinant human 4-1BB ligand, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography, 23.8 kDa (222aa).
||4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily.4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease.
|Sequences of amino acids :
||MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTG GLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRL GVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPAGLPSPR SE
||> 95% by SDS - PAGE
||Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol
||1 mg/ml (determined by Bradford assay)
||Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.