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Recombinant Human Ubiquitin-Conjugating Enzyme E2L6, His-tagged

Cat.No. : UBE2L6-30H
Product Overview : Recombinant human UBE2L6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 21.7kDa (188aa).
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Cat. No. : UBE2L6-30H
Description : Ubiquitin-conjugating enzyme E2L6 (UBE2L6), also known as UbcH8, is a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination of a protein substrate requires the concerted action of 3 classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin protein ligases. The E2 ubiquitin-conjugating enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene.
Source : Escherichia Coli.
Form : Liquid in 20mM Tris pH 8.0, 1 mM DTT, 0.1 mM PMSF 10% glycerol.
Purity : > 90% by SDS PAGE.
Concentration : 1 mg/ml (determined by Bradford assay)
Sequences of amino acids : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMASM RVVKE LEDLQ KKPPPYLRNL SSDDANVLVW HALLLPDQPP YHLKAFNLRI SFP PEYPFKP PMIKFTTKIY HPNVDENGQI CLPIISSENW KPCTKTCQVL EALN VLVNRP NIREPLRMDL ADLLTQNPEL FRKNAEEFTL RFGVDRPS
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : UBE2L6 ubiquitin-conjugating enzyme E2L 6 [ Homo sapiens ]
Synonyms : ubiquitin-conjugating enzyme E2L 6; RIG-B; UBCH8; MGC40331; UBE2L6; ubiquitin-protein ligase; ubiquitin carrier protein; retinoic acid induced gene B protein; EC 6.3.2.19; MGC40331; Retinoic acid-induced gene B protein; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6; ubiquitin-protein ligase.
Gene ID : 9246
mRNA Refseq : NM_004223
Protein Refseq : NP_004214
MIM : 603890
UniProt ID : O14933
Chromosome Location : 11q12
Function : ligase activity; protein binding; ubiquitin-protein ligase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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