"UBE2L6" Related Products

Recombinant Human Ubiquitin-Conjugating Enzyme E2L6, His-tagged

Cat. No. : UBE2L6-30H
Product Overview : Recombinant human UBE2L6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 21.7kDa (188aa).
Description : Ubiquitin-conjugating enzyme E2L6 (UBE2L6), also known as UbcH8, is a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination of a protein substrate requires the concerted action of 3 classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin protein ligases. The E2 ubiquitin-conjugating enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene.
Source : Escherichia Coli.
Form : Liquid in 20mM Tris pH 8.0, 1 mM DTT, 0.1 mM PMSF 10% glycerol.
Purity : > 90% by SDS PAGE.
Concentration : 1 mg/ml (determined by Bradford assay)
Sequences of amino acids : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMASM RVVKE LEDLQ KKPPPYLRNL SSDDANVLVW HALLLPDQPP YHLKAFNLRI SFP PEYPFKP PMIKFTTKIY HPNVDENGQI CLPIISSENW KPCTKTCQVL EALN VLVNRP NIREPLRMDL ADLLTQNPEL FRKNAEEFTL RFGVDRPS
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : UBE2L6 ubiquitin-conjugating enzyme E2L 6 [ Homo sapiens ]
Synonyms : ubiquitin-conjugating enzyme E2L 6; RIG-B; UBCH8; MGC40331; UBE2L6; ubiquitin-protein ligase; ubiquitin carrier protein; retinoic acid induced gene B protein; EC 6.3.2.19; MGC40331; Retinoic acid-induced gene B protein; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6; ubiquitin-protein ligase.
Gene ID : 9246
mRNA Refseq : NM_004223
Protein Refseq : NP_004214
MIM : 603890
UniProt ID : O14933
Chromosome Location : 11q12
Function : ligase activity; protein binding; ubiquitin-protein ligase activity

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