"VEGFB" Related Products

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Recombinant Human Vascular Endothelial Growth Factor B, His-tagged

Cat. No.: VEGFB-128H
Product Overview: Recombinant human VEGF-B protein was expressed in E.coli and purified by using conventional chromatography techniques, 21.6 kDa (207 aa).
Description: VEGF-B, also known as Vascular endothelial growth factor-B, is one of 5 mammalian VEGF family members, the others being VEGF-A, VEGF-C, VEGF-D, and placental growth factor (PlGF). VEGF-B binds to one of the VEGF receptor tyrosine kinases, namely VEGF receptor-1(VEGFR1, Flt1), but not to VEGFR2 and VEGFR3. VEGF-B is homodimeric, heparin-binding glycoprotein involved in embryonic angiogenesis and vasculogenesis.
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MPVSQPDAPG HQRKVVSWID VYTRATCQPR EVVVPLTVEL MGTVAKQLVP SCVTVQRCGG CCPDDGLECV PTGQHQVRMQ ILMIRYPSSQ LGEMSLEEHS QCECRPKKKD SAVKPDRAAT PHHRPQPRSV PGWDSAPGAP SPADITHPTP APGPSAHAAP STTSALTPGP AAAAADAAAS SVAKGGA
Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 10% glycerol
Purity: > 90% by SDS - PAGE
Concentration: 1 mg/ml (determined by Bradford assay)
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: VEGFB vascular endothelial growth factor B [ Homo sapiens ]
Synonyms: VEGF-B; VEGFL; VRF; VEGF-related factor; vascular endothelial growth factor B; VEGFB;VEGF-related factor (VRF)
Gene ID: 7423
mRNA Refseq: NM_003377
Protein Refseq: NP_003368
MIM: 601398
UniProt ID: P49765
Chromosome Location: 11q13
Pathway: Cytokine-cytokine receptor interaction; Focal adhesion; Pancreatic cancer; Renal cell carcinoma; mTOR signaling pathway; Hemostasis; Signaling by VEGF
Function: growth factor activity; heparin binding; protein binding; vascular endothelial growth factor receptor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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