"YWHAZ" Related Products

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Recombinant Human Tyrosine 3-monooxygenase/ Tryptophan 5-monooxygenase Activation Protein, Zeta Polypeptide, His-tagged

Cat. No. : YWHAZ-104H
Product Overview : Recombinant human YWHAZ, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (245 aa, 32kDa).
Description : The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. 14-3-3 zeta interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity.
Source : E.coli.
Formulation : Liquid in Phosphate Buffered Saline pH7.4.
Molecular Weight : 32 kDa (245 aa).
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequence : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMDK NELVQKAKLA EQAERYDDMA ACMKSVTEQG AELSNEERNL LSVAYKNVVG ARRSSWRVVS SIEQKTEGAE KKQQMAREYR EKIETELRDI CNDVLSLLEK FLIPNASQAE SKVFYLKMKG DYYRYLAEVA AGDDKKGIVD QSQQAYQEAF EISKKEMQPT HPIRLGLALN FSVFYYEILN SPEKACSLAK TAFDEAIAEL DTLSEESYKD STLIMQLLRD NLTLWTSDTQ GDEAEAGEGG EN
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : YWHAZ
Synonyms : YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; KCIP-1; MGC111427; MGC126532; MGC138156; phospholipase A2; 14-3-3 zeta; 14-3-3 protein/cytosolic phospholipase A2; Protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; OTTHUMP00000165851; OTTHUMP00000165852; OTTHUMP00000165854; OTTHUMP00000165858; OTTHUMP00000165859; OTTHUMP00000165860; YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide.
Gene ID : 7534
mRNA Refseq : NM_001135699.1
Protein Refseq : NP_001129171.1
MIM : 601288
UniProt ID : P63104
Chromosome Location : 8q23.1
Pathway : Cell cycle; Pathogenic Escherichia coli infection - EHEC; Pathogenic Escherichia coli infection - EPEC.
Function : protein domain specific binding; transcription factor binding.

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