"tcdA" Related Products

Native C. difficile Toxin A

Cat.No.: tcdA-4809C
Product Overview: Native Toxin A was purified from Clostridium difficile.
Description: Clostridium difficile toxin A (TcdA) is a toxin generated by Clostridium difficile. It is similar to Clostridium difficile Toxin B. The toxins are the main virulence factors produced by the gram positive, anaerobic, Clostridium difficile bacteria. The toxins function by damaging the intestinal mucosa and cause the symptoms of C. difficile infection, including pseudomembranous colitis.
Source: C. difficile
Species: C. difficile
Bio-activity: Each lot of C. difficile toxin A is tested to confirm binding activity to fresh rabbit red blood cells using a hemagglutination assay
Molecular Mass: This preparation migrated as a single major band of molecular weight> 200,000 daltons and several minor aggregate bands when run on a 3-8% gradient polyacrylamide-SDS gel.
Notes: FOR RESEARCH PURPOSES ONLY. NOT FOR HUMAN USE.
Storage: This product is packaged aseptically, lyophilized, and sealed under vacuum. Store at 2-8ºC prior to reconstitution. Following reconstitution, use immediately; Do not store. Do not freeze.
Concentration: Protein concentration is determined by the Bradford method using bovine serum albumin as the standard.
Reconstitution: Each vial, when reconstituted with 0.5 ml of sterile purified water, contains 100 ug of C. difficile toxin A enterotoxin in 50 mM Tris, pH 7.5, 50 mM NaCl, and 0.1 % trehalose. Handle product gently; do not vortex.
Gene Name: tcdA toxin A [ Clostridium difficile R20291 ]
Official Symbol: tcdA
Synonyms: tcdA; toxin A
Gene ID: 8470358
Protein Refseq: YP_003217088

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