"FGF7" Related Products

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Recombinant Human Fibroblast growth factor 7

Cat.No.: FGF7-01H
Antigen Description: Keratinocyte Growth Factor-1 (KGF-1/FGF-7) is one of 23 known members of the FGF family. All FGFs have two conserved cysteine residues and share 30.50% sequence identity at the amino acid level. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF-1/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF-1/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing.
Source: E.coli
Species: Human
Form: 20 mM PBS, pH7.4, 5%Trehalose
Bio-activity: The biological activity was determined by the does-dependent stimulation of thymidine uptake by BaF3 cells expressing KGF receptors yielding an ED50<10ng>
Molecular Mass: Approximately 19.0 kDa
Endotoxin: Less than 1EU/mg of rHuFGF-7 as determined by LAL method.
Purity: >95% as determined by SDS-PAGE
Storage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into sterile distilled water or working aliquots with 20% glycerol or 0.1% BSA and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Reconstitution: Reconstitute in sterile distilled water or aqueous buffer containing 20% glycerol or 0.1% BSA to a concentration of 0.1-1.0mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20°C to -70°C. Further dilutions should be made in appropriate buffered solutions.
Gene Name: FGF7 fibroblast growth factor 7 [ Homo sapiens ]
Official Symbol: FGF7
Synonyms: FGF7; fibroblast growth factor 7; KGF; HBGF-7; FGF-7; keratinocyte growth factor; heparin-binding growth factor 7; fibroblast growth factor 7 (keratinocyte growth factor); OTTHUMP00000162252
Gene ID: 2252
mRNA Refseq: NM_002009
Protein Refseq: NP_002000
MIM: 148180
UniProt ID: P21781
Chromosome Location: 15q21.2
Pathway: MAPK signaling pathway; Melanoma; Prostate cancer; Regulation of actin cytoskeleton; Signaling by FGFR
Function: growth factor activity; chemoattractant activity; heparin binding; type 2 fibroblast growth factor receptor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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