"IL2" Related Products

Human IL-2/Diphtheriae diphtheria toxin fragments A and B, His-tagged Stable Cell Line-CHO

Cat.No.: CSC-TP036
Product Overview: CHO-Corynebacterium Diphtheriae diphtheria toxin fragments A and B & Human IL-2, His-tagged Stable Cell Line(Denileukin diftitox) is clonally-derived from a CHO cell line, which has been transfected with diphtheria toxin and IL2 gene to allow expression of the protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133).
Description: The expression product is the active ingredient of Ontak.
Source: CHO
Species: Human
Tag : His
Molecular Mass: 57.6 kDa
Protein length: 401 Aa
Endotoxin: < 1.0 EU per μg of the protein
Purity: >96%
Notes: Growth Properties: Adherent;
Morphology: Epithelial-like.
Gene Name: IL2 interleukin 2 [ Homo sapiens ]
Official Symbol: IL-2
Synonyms: IL-2; TCGF; lymphokine; T cell growth factor; aldesleukin; involved in regulation of T-cell clonal expansion
Gene ID: 3558
mRNA Refseq: NM_000586
Protein Refseq: NP_000577
MIM: 147680
UniProt ID: P60568
Chromosome Location: 4q27
Pathway: ARMS-mediated activation, organism-specific biosystem; Allograft rejection, conserved biosystem; Axon guidance, organism-specific biosystem
Function: carbohydrate binding; interleukin-2 receptor binding; kinase activator activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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