Active Recombinant Human DLL1

• Cat.No.: DLL1-286H
• Product Overview: Recombinant Human DLL1 (Accession # AAG09716) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Predicted N Terminal: Ser22 & His152
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to enhance BMP-2 induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. Nobta, M. et al. (2005) J. Biol. Chem. 280:15842.The ED50 for this effect is typically 0.25 - 1.0 µg/mL.
• Molecular Mass: Recombinant Human DLL1 has a calculated MW of 57 kDa and 43 kDa. In SDS-PAGE migrates as 66 kDa and 55 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: DLL1 delta-like 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: DLL1
• Synonyms: DLL1; delta-like 1 (Drosophila); delta (Drosophila) like 1; delta-like protein 1; H-Delta-1; drosophila Delta homolog 1; DL1; Delta; DELTA1
• Gene ID: 28514
• mRNA Refseq: NM_005618
• Protein Refseq: NP_005609
• MIM: 606582
• UniProt ID: O00548
• Chromosome Location: 6q13-q22.33