Active Recombinant Human CD163, His-tagged

• Cat.No.: CD163-510H
• Product Overview: Recombinant Human CD163 (Accession # CAA80543) Gly41-Ser1045, fused with a C-terminal 10-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: His
• Predicted N Terminal: Gly41
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind Haptoglobin/Hemoglobin (Hp/Hb) complexes. Kristiansen, M. et al. (2001) Nature 409:198.
• Molecular Mass: Recombinant Human CD163, His-tagged has a calculated MW of 110 kDa. In SDS-PAGE migrates as 135-140 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: CD163 CD163 molecule [ Homo sapiens ]
• Official Symbol: CD163
• Synonyms: CD163; CD163 molecule; CD163 antigen; scavenger receptor cysteine-rich type 1 protein M130; M130; MM130; hemoglobin scavenger receptor; macrophage-associated antigen
• Gene ID: 9332
• mRNA Refseq: NM_004244
• Protein Refseq: NP_004235
• MIM: 605545
• UniProt ID: Q86VB7
• Chromosome Location: 12p13