Active Recombinant Human ADAMTS13 protein, His-tagged

• Cat.No.: ADAMTS13-820H
• Product Overview: Recombinant Human ADAMTS13(Gln34-Thr1427) fused with His tag at C-terminal was expressed in CHO.

Specification

• Source: CHO
• Species: Human
• Tag: His
• Predicted N Terminal: Ala75
• Form: Supplied as a 0.2 μm filtered solution in Sodium Acetate, NaCl and Brij-35.
• Bio-activity: Measured by its ability to cleave the fluorogenic peptide substrate, FRETS-VWF73. The specific activity is >10 pmol/min/μg.
• Molecular Mass: Predicted Molecular Mass: 147 kDa;
  SDS-PAGE: 160-180 kDa, reducing conditions.
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Avoid repeated freeze-thaw cycles.
  6 months from date of receipt, -20 to -70 centigrade as supplied.
  3 months, -20 to -70 centigrade under sterile conditions after opening.

Gene Information

• Gene Name: ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 [ Homo sapiens ]
• Official Symbol: ADAMTS13
• Synonyms: ADAMTS13; ADAM metallopeptidase with thrombospondin type 1 motif, 13; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , C9orf8; A disintegrin and metalloproteinase with thrombospondin motifs 13; DKFZp434C2322; FLJ42993; MGC118899; MGC118900; TTP; vWF CP; VWFCP; ADAM-TS 13; vWF-cleaving protease; von Willebrand factor-cleaving protease; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13; 13; C9orf8; vWF-CP; ADAM-TS; ADAM-TS13; ADAMTS-13
• Gene ID: 11093
• mRNA Refseq: NM_139025
• Protein Refseq: NP_620594
• MIM: 604134
• UniProt ID: Q76LX8
• Chromosome Location: 9q34
• Function: calcium ion binding; integrin binding; metalloendopeptidase activity; metallopeptidase activity; metallopeptidase activity; peptidase activity; protein binding; zinc ion binding; zinc ion binding