Active Recombinant Human IL37

• Cat.No.: IL37-853H
• Product Overview: Recombinant Human IL37 (Accession # NP_775297) Lys27-Asp192, fused with an N-terminal Met, was produced in E. coli.

Specification

• Source: E. coli
• Species: Human
• Predicted N Terminal: Met
• Form: Lyophilized from a 0.2 µm filtered solution in PBS and DTT.
• Bio-activity: Measured by its binding ability in a functional ELISA.Immobilized Recombinant Human (rh) IL-37/IL-1F7 at 0.1 µg/mL (100 µL/well) can bind rhIL-18 R Fc Chimera with a linear range of 0.015-1 µg/mL.
• Molecular Mass: Recombinant Human IL37, Met-tagged has a calculated MW of 18.6 kDa.
• Protein length: Lys27-Asp192
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Publication:
  Anti-Inflammatory Effect of IL-37b in Children with Allergic Rhinitis (2014)

Gene Information

• Gene Name: IL37 interleukin 37 [ Homo sapiens ]
• Official Symbol: IL37
• Synonyms: IL37; interleukin 37; IL1F7, interleukin 1 family, member 7 (zeta); interleukin-37; FIL1; FIL1(ZETA); FIL1Z; IL 1F7; IL 1H4; IL 1RP1; interleukin 1; zeta; interleukin 1 homolog 4; interleukin 1 related protein; FIL1 zeta; IL-1 zeta; IL-1X protein; interleukin-23; interleukin 1, zeta; interleukin-1 homolog 4; interleukin-1 superfamily z; interleukin 1 family member 7; interleukin-1-related protein; IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL1F7 (canonical product IL-1F7b); IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1
• Gene ID: 27178
• mRNA Refseq: NM_014439
• Protein Refseq: NP_055254
• MIM: 605510
• UniProt ID: Q9NZH6
• Chromosome Location: 2q12-q14.1