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Active Recombinant Human FN1 Protein, His-tagged

Cat.No. : FN1-882H
Product Overview : Recombinant Human FN1 (Accession # NP_997647) Val1913-Glu2477, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.
  • Specification
  • Gene Information
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Source : Mammalian cells
Species : Human
Tag : His
Predicted N Terminal : Val1913
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of B16-F1 mouse melanoma cells.When 5 x 10^4 cells/well are added to rhFN1.4 coated plates (3 µg/mL and 100 µL/well), approximately 60 - 80% will adhere after 30 minutes at 37° C.
Molecular Mass : Recombinant Human FN1, His-tagged has a calculated MW of 63.5 kDa. In SDS-PAGE migrates as 70-95 kDa, reducing conditions.
Protein length : Val1913-Glu2477
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : FN1 fibronectin 1 [ Homo sapiens ]
Official Symbol : FN1
Synonyms : FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;
Gene ID : 2335
mRNA Refseq : NM_002026
Protein Refseq : NP_002017
MIM : 135600
UniProt ID : P02751
Chromosome Location : 2q34

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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which organs and tissues is the FN1 protein expressed? 12/21/2019

It is expressed in a variety of organs and tissues, including skin, kidneys, cardiovascular system, liver, etc.

How about the FN1 protein in inflammatory diseases? 09/09/2019

FN1 protein is involved in the migration, adhesion and activation of inflammatory cells during the inflammatory response, and plays an important role in the development of inflammation.

Have regulators of the FN1 protein been identified? 07/16/2019

Yes, multiple factors have been found to regulate the expression and function of FN1 protein, including transcription factors, growth factors, etc.

What is the relationship between FN1 protein and tumor metastasis? 06/26/2019

FN1 protein is involved in the invasion and metastasis of tumor cells, which can provide matrix support and guide signals to promote the migration and invasion of tumor cells.

What is the role of FN1 protein in wound healing? 04/15/2019

This protein is involved in key steps such as fibrosis, angiogenesis and interstitial cell proliferation in the wound healing process, and plays an important role in wound repair.

How about the mechanism of action of FN1 protein in tissue repair? 04/13/2019

The protein plays an important role in key steps such as extracellular matrix remodeling, cell adhesion, and directed differentiation of mesenchymal stem cells during tissue repair.

Customer Reviews (3)

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Reviews
06/21/2021

    The preservation conditions are wide and the efficiency is high.

    08/14/2019

      Experimental process is convenient, which greatly improves the efficiency of scientific research.

      03/25/2019

        Biological activity of this protein is amazing, and you can see that its production process is very pure, which has a crucial effect on the quality of the product.

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