Recombinant Human TLR4 TLR4-887H

Recombinant Human TLR4

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Recombinant Human TLR4

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Cat.No. : TLR4-887H
Product Overview : Recombinant Human TLR4 (Accession # O00206), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO Cells
Species : Human
Predicted N Terminal : Glu24 (TLR4) & Glu17 (MD-2)
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to inhibit LPS-induced TNF-alpha secretion by PMA-differentiated U937 human histiocytic lymphoma cells.Typically 20 µg/mL of rhTLR4/MD-2 will inhibit >60% of the TNF-alpha secretion induced by 10 ng/mL of LPS.
Molecular Mass : Recombinant Human TLR4 has a calculated MW of 70.6 kDa (TLR4), 19.2 kDa (MD-2). In SDS-PAGE migrates as 95 kDa and 34 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : TLR4 toll-like receptor 4 [ Homo sapiens ]
Official Symbol : TLR4
Synonyms : TLR4; toll-like receptor 4; CD284; hToll; TLR 4; homolog of Drosophila toll; TOLL; TLR-4; ARMD10;
Gene ID : 7099
mRNA Refseq : NM_003266
Protein Refseq : NP_003257
MIM :
UniProt ID : O00206
Chromosome Location : 9q33.1

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