Recombinant Human TLR4


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Recombinant Human TLR4

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Cat.No. : TLR4-887H
Product Overview : Recombinant Human TLR4 (Accession # O00206), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO Cells
Species : Human
Predicted N Terminal : Glu24 (TLR4) & Glu17 (MD-2)
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to inhibit LPS-induced TNF-alpha secretion by PMA-differentiated U937 human histiocytic lymphoma cells.Typically 20 µg/mL of rhTLR4/MD-2 will inhibit >60% of the TNF-alpha secretion induced by 10 ng/mL of LPS.
Molecular Mass : Recombinant Human TLR4 has a calculated MW of 70.6 kDa (TLR4), 19.2 kDa (MD-2). In SDS-PAGE migrates as 95 kDa and 34 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : TLR4 toll-like receptor 4 [ Homo sapiens ]
Official Symbol : TLR4
Synonyms : TLR4; toll-like receptor 4; CD284; hToll; TLR 4; homolog of Drosophila toll; TOLL; TLR-4; ARMD10;
Gene ID : 7099
mRNA Refseq : NM_003266
Protein Refseq : NP_003257
UniProt ID : O00206
Chromosome Location : 9q33.1
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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