"HDAC8" Related Products

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Recombinant Human Histone Deacetylase 8, GST-tagged

Cat. No. : HDAC8-399H
Product Overview : Full Length Human HDAC8 (NM_003883) – Class I, 70kD withGST tag.
Description : Histone deacetylase 8, also known as HDAC8, is a human gene. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
Source : HDAC8 was cloned from human brain cDNA and expressed in insect cells using a baculoviral expression system.
Purity : Purified, active enzyme.
Purification Procedure : Glutathione column
Activity : 1000 units per vial.1 unit is defined as the amount of enzyme that will convert 1picomole per minute per ug of protein at pH8 at 30°C.
Stability/Shelf-life : >6 months from date of shipment
Buffer Composition : 25mM Tris pH8, 120mM NaCl, 0.05% Tween-20 & 40% Glycerol
Storage : –80°C
Gene Name : HDAC8 histone deacetylase 8 [ Homo sapiens ]
Synonyms : HDAC8; RPD3; HDACL1; histone deacetylase 8; histone deacetylase-like 1; EC 3.5.1.98; HD8.
Gene ID : 55869
mRNA Refseq : NM_018486
Protein Refseq : NP_060956
MIM : 300269
UniProt ID : Q9BY41
Chromosome Location : Xq13
Pathway : Gene Expression
Function : histone deacetylase activity; hydrolase activity; transcription factor binding

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