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Recombinant Mouse Interferon Beta 1, Fibroblast, His-tagged

Cat. No. : Ifnb1-108M
Product Overview : Recombinant Mouse Interferon beta 1 protein was expressed in E.coli and purified by using conventional chromatography techniques, 22.0 kDa (182 aa) with his tag.
Description : Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis.
Source : Escherichia Coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1 M NaCl, 30% glycerol
Purity : > 95% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Endotoxin Level : < 1.0 EU per 1 μg of protein (determined by LAL method )
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : Ifnb1 interferon beta 1, fibroblast [ Mus musculus ]
Synonyms : Ifnb1; interferon beta 1, fibroblast; Ifb; IFNB; IFN-beta; OTTMUSP00000008111; IFB; IFF; IFN-beta; MGC96956; OTTHUMP00000021131; Fibroblast interferon; interferon beta; interferon, beta 1, fibroblast.
Gene ID : 15977
mRNA Refseq : NM_010510
Protein Refseq : NP_034640
UniProt ID : P01575
Chromosome Location : 4 C4; 4 42.6 cM
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; Toll-like receptor signaling pathway
Function : cytokine activity; cytokine receptor binding

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