Recombinant Human IL2RA protein, His-tagged

Cat.No.: IL2RA-99H
Product Overview: Recombinant Human IL2RA(22-213 aa) fused with His tag was expressed in E. coli.
Description: IL2-Ra is one of the three constituent subunits of the IL2 receptor.IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas.
Source: E. coli
Species: Human
Tag: His
Form: Supplied in 1x PBS and 50% glycerol pH 7.4.
Purity: Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Stability: Store at 4 centigrade if entire vial will be used within 2-4 weeks.Store, frozen at -20 centigrade for longer periods of time.Please avoid freeze thaw cycles.
Gene Name: IL2RA interleukin 2 receptor, alpha [ Homo sapiens ]
Official Symbol: IL2RA
Synonyms: IL2RA; interleukin 2 receptor, alpha; IL2R; interleukin-2 receptor subunit alpha; CD25; p55; IL2-RA; IL-2-RA; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; TCGFR; IDDM10;
Gene ID: 3559
mRNA Refseq: NM_000417
Protein Refseq: NP_000408
MIM: 147730
UniProt ID: P01589
Chromosome Location: 10p15-p14
Pathway: Arf6 trafficking events, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem;
Function: drug binding; interleukin-2 binding; interleukin-2 receptor activity; receptor activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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