||Recombinant Human annexin 9 produced inE.coliis a non-glycosylated, polypeptide chain containing amino acids (1-338) and having a total molecular mass of 38.9 kDa. rhANXA9 contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.
||The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. The most striking feature of annexin 31 is a complete ablation of all four homologous type II calcium-binding sites in the conserved tetrad core. Although all 4 type II calcium-binding sites in annexin 31 contained amino acid substitutions that ablated their function, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.
||Sterile Filtered clear solution.
||Greater than 95.0% as determined by the analysis by reducing and non-reducing SDS-PAGE coomassie blue staining.
||Recombinant Human Annexin-9 at a concentration of 0.1mg containing 10 mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
||•ELISA • MS• Western Blotting.
||RhAnnexin-9 although stable at 14°Cfor 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.