||Recombinant Human progesterone receptor protein expressed inE.coliencodes 412-562 amino acids and has a molecular mass of 43 kDa.
||The progesterone receptor (PgR) is an estrogen-regulated protein. It has been proposed that expression of PgR determination indicates a responsive estrogen receptor (ER) pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer. A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival. PgR has proved superior to ER as a prognostic indicator in some studies.
||Recombinant Human PGR at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
|Application And Suggested Dilutions:
||•ELISA •Inhibition Assays •Western Blotting.
||On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 43 kDa.
|Storage & Stability:
||Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.