"TANK" Related Products

Expand
Expand

Recombinant Human TANK

Cat. No. : TANK-517H
Product Overview : Recombinant human TANK protein was expressed inE.coliand purified by using conventional chromatography techniques. 13.6 kDa (119 aa).
Description : TANK, also known as TRAF(tumor necrosis factor receptor-associated Factor)-interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1.
Source : E.coli.
Amino Acid Sequence : MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIA SAESSI.
Form : Liquid. In 20mM Tris-HCl buffer (pH8.0).
Purity : > 90% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : TANK TRAF family member-associated NFKB activator [ Homo sapiens ]
Synonyms : TANK; TRAF family member-associated NFKB activator; TRAF2; I-TRAF;TRAF interacting protein TANK; TRAF family member-associated NF-KAPPA-B activator; TRAF-interacting protein; I-TRAF; TRAF interacting protein
Gene ID : 10010
mRNA Refseq : NM_004180
Protein Refseq : NP_004171
MIM : 603893
UniProt ID : Q92844
Chromosome Location : 2q24-q31
Pathway : RIG-I-like receptor signaling pathway
Function : metal ion binding; protein binding; zinc ion binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.