"TNFSF13B" Related Products

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Recombinant Human TNFSF13B, His-tagged

Cat. No. : TNFSF13B-184H
Product Overview : Recombinant human BLyS, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 21 kDa (190 aa).
Description : B lymphocyte stimulator (BLyS), a member of the tumor necrosis factor (TNF) superfamily of cytokines, induces B-cell proliferation and immunoglobulin secretion and is a key regulator of peripheral B-cell populations in vivo.BLyS is made by immune-cells called monocytes and macrophages. When monocytes and macrophages are activated, BLyS is released and binds to a receptor found only on B cells.
Source : E.coli.
Amino Acid Sequence : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAV QGPEETVTQD CLQLIADSET PTIQKGSYTF VPWLLSFKRG SALEEKENKI LVKETGYFFI YGQVLYTDKT YAMGHLIQRK KVHVFGDELS LVTLFRCIQN MPETLPNNSC YSAGIAKLEE GDELQLAIPR ENAQISLDGD VTFFGALKLL.
Form : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 5 mM DTT.
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b [ Homo sapiens ]
Synonyms : TNFSF13B; tumor necrosis factor (ligand) superfamily, member 13b; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; TNFSF13B; Tumor necrosis factor ligand superfamily member 13B; TNF- and APOL-related leukocyte expressed ligand 1; B lymphocyte stimulator; B cell-activating factor; Dendritic cell-derived TNF-like moleculeCD_antigen=CD257; Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form
Gene ID : 10673
mRNA Refseq : NM_001145645
Protein Refseq : NP_001139117
MIM : 603969
UniProt ID : Q9Y275
Chromosome Location : q32-q34
Pathway : tokine-cytokine receptor interaction
Function : cytokine activity; tumor necrosis factor receptor binding

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