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Recombinant Influenza A H5N1 HA, His tagged

Cat.No. : HA-734I
Product Overview : Recombinant Influenza A H5N1 HA (A/bar-headed goose/Qinghai/14/2008 (H5N1)) (ACL28277.1) extracellular domain HA (Met 1-Gln 531)with cleavage site mutated (RERRRKKR → TETR, HA1+HA2, uncleaved), fused with a C-terminal polyhistidine tag, was produced in Hu
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  • Gene Information
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Source : Human Cells
Species : Influenza A H5N1
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The secreted recombinant hemagglutinin of Influenza A virus H5N1 (A/bar-headed goose/Qinghai/14/2008) comprises 522 amino acids with the predicted molecular mass of 59.5 kDa. As a result of glycosylation, it migrates as an approximately 70 kDa band in Non-reduced SDS-PAGE and also exists as polymers.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : HA hemagglutinin [ Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) ]
Official Symbol : HA
Gene ID : 3654620
Protein Refseq : YP_308669
UniProt ID : Q9Q0U6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How about the structural characteristics of HA protein? 09/14/2019

HA protein is a glycoprotein that contains thousands of carbohydrates and an amino acid chain consisting of 566 amino acid residues. The structure of HA protein has triple symmetry, consisting of three monomers that form a spiral.

Will genetic variants in HA proteins affect vaccine development? 06/06/2019

Genetic variants in the HA protein may affect the development and production of influenza vaccines. Because HA protein is an important component of influenza viruses, different subtypes or variants of HA protein may require different vaccines to prepare.

Why is hemagglutinin protein related to viral replication? 05/17/2019

This protein is one of the key factors in the replication process of influenza viruses. When a virus infects a host cell, the receptor-binding region of the HA protein binds to the receptor on the cell surface, allowing the virus to invade the host cell and replicate.

What are the subtypes of HA protein? 04/01/2019

There are currently 18 known HA subtypes of influenza viruses, H1-H18. Among them, the H1, H2, H3, H5, H7, and H9 subtypes are associated with human viruses, while other subtypes are generally associated with animal viruses.

What are the physiological functions of HA protein? 03/07/2019

The main physiological function of HA protein is to bind to host cells and mediate the entry of influenza viruses into host cells. It contains specific regions that bind glycoprotein receptors that allow the influenza virus to adhere to them. This is an important link that allows the virus to stably bind and enter the cell.

What laboratory techniques are HA proteins used in? 01/07/2019

HA protein is widely used in viral research and drug development. Researchers can use HA proteins to test drugs such as influenza virus activators, antibodies and vaccines, and HA proteins are also widely used to develop novel immunoassays and treatments.

Customer Reviews (2)

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Reviews
06/01/2021

    The transport process does not affect the protein quality, and the stability is good.

    11/27/2019

      Higher solubility makes it easy to prepare the desired concentration.

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