Recombinant Human MMP7, Fc tagged
Cat.No. : | MMP7-810H |
Product Overview : | Recombinant Human MMP7 active form (NP_002414.1) (Tyr 95-Lys 267), fused with the Fc region of human IgG1 at the N-terminus, was produced in Human Cell. |
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Source : | Human Cells |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5 |
Molecular Mass : | The recombinant human Fc/MMP7 chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 410 amino acids and predicts a molecular mass of 45.8 kDa. As a result of glycosylation, the rh Fc/MMP7 monomer migrates as an approximately 55 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | MMP7 matrix metallopeptidase 7 (matrilysin, uterine) [ Homo sapiens ] |
Official Symbol : | MMP7 |
Gene ID : | 4316 |
mRNA Refseq : | NM_002423 |
Protein Refseq : | NP_002414 |
MIM : | 178990 |
UniProt ID : | P09237 |
Products Types
◆ Recombinant Protein | ||
MMP7-1125C | Recombinant Chicken MMP7 Protein, His&GST-tagged | +Inquiry |
MMP7-1458R | Recombinant Rat MMP7 Protein (98-267 aa), His-tagged | +Inquiry |
MMP7-5435H | Recombinant Human MMP7 Protein, GST-tagged | +Inquiry |
MMP7-50H | Active Recombinant Human MMP7 Protein, TG-8H-GGQ-tagged | +Inquiry |
MMP7-1126C | Recombinant Cattle MMP7 Protein, His&GST-tagged | +Inquiry |
◆ Native Protein | ||
MMP7-28205TH | Native Human MMP7 | +Inquiry |
◆ Lysates | ||
MMP7-2883HCL | Recombinant Human MMP7 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionMMP7 overexpression has been linked to various diseases, including cancer, inflammatory disorders, and tissue fibrosis.
MMP7 is involved in the degradation of extracellular matrix components during inflammation, influencing tissue damage and repair processes.
Developing specific inhibitors that target MMP7 activity is a potential approach for therapeutic interventions, particularly in diseases where MMP7 plays a detrimental role.
Several MMP inhibitors have been investigated, and some show promise in controlling MMP7 activity. However, their clinical use is still under research.
MMP7 facilitates cancer cell invasion and metastasis by degrading the extracellular matrix, allowing cancer cells to invade surrounding tissues and spread to distant organs.
Yes, elevated levels of MMP7 have been observed in the serum or tissues of cancer patients, making it a potential biomarker for certain types of cancer.
Customer Reviews (3)
Write a reviewThis includes rigorous quality control measures to ensure the consistency and purity of the protein, thereby reducing variability in the experimental outcomes.
by utilizing MMP7 protein in trials and collaborating with a supportive manufacturer, researchers can gain access to a versatile tool that can aid in their understanding of angiogenesis and vascular biology.
With expert assistance and reliable product quality, researchers can conduct their experiments with confidence, enabling them to contribute to advancements in the field and potentially improve future therapeutic interventions.
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