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Recombinant Human MSR1 protein, His-tagged

Cat.No. : MSR1-872H
Product Overview : Recombinant Human MSR1 protein(NP_619729.1)(Lys77-Leu451), fused with His tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.5Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human MSR1 consisting of 391 amino acids predicts a molecular mass of 43 kDa. Due to glycosylation, apparent molecular mass of rh MSR1 is approximately 55-65 kDa in SDS-PAGE under reducing conditions.
Protein Length : Lys77-Leu451
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : MSR1 macrophage scavenger receptor 1 [ Homo sapiens ]
Official Symbol : MSR1
Synonyms : MSR1; macrophage scavenger receptor 1; macrophage scavenger receptor types I and II; CD204; SCARA1; scavenger receptor class A member 1; scavenger receptor class A, member 1; macrophage scavenger receptor type III; macrophage acetylated LDL receptor I and II; SRA; SR-A; phSR1; phSR2;
Gene ID : 4481
mRNA Refseq : NM_138716
Protein Refseq : NP_619730
MIM : 153622
UniProt ID : P21757

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the primary function of the MSR1 protein, and in which cellular processes does it play a crucial role? 09/24/2020

MSR1 (Macrophage Scavenger Receptor 1) is involved in the recognition and clearance of modified low-density lipoproteins (LDL) by macrophages, playing a critical role in lipid homeostasis.

How does MSR1 contribute to the resolution of inflammation, and what mechanisms are involved in its anti-inflammatory effects? 02/10/2020

MSR1 contributes to the resolution of inflammation by promoting the clearance of apoptotic cells and debris. Its anti-inflammatory effects involve modulating cytokine production and signaling.

What role does MSR1 play in antigen presentation and T-cell activation within the immune system? 06/21/2019

MSR1 participates in antigen presentation by macrophages, influencing T-cell activation. This role connects MSR1 to adaptive immune responses.

What is the relationship between MSR1 and the clearance of amyloid-beta peptides, and how does this link to neurodegenerative diseases? 10/13/2018

MSR1 is involved in the clearance of amyloid-beta peptides associated with neurodegenerative diseases such as Alzheimer's. Its role in phagocytosis and clearance is crucial in the context of neuroinflammation.

How does MSR1 contribute to the immune response, and what are its implications in the context of inflammation and atherosclerosis? 01/31/2018

MSR1 modulates the immune response by regulating inflammatory signaling pathways. Its involvement in recognizing modified LDL in atherosclerotic plaques links it to inflammation and atherosclerosis.

Customer Reviews (3)

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Reviews
03/19/2022

    No more worries about protein sourcing. This product is a lifesaver in the lab.

    07/03/2020

      Outstanding service! Quick response to inquiries and prompt shipping. A+

      10/26/2019

        This is a must-have in any lab. Consistent quality and great results every time.

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