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Active Recombinant Human NCR3 protein, His-tagged

Cat.No. : NCR3-816H
Product Overview : Recombinant Human NCR3 protein(NP_667341.1)(Met1-Gly135), fused with His tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized human NCR3 at 10μg/mL (100μL/well) can bind human B7-H6, the EC50 of human B7-H6 is 20-100ng/mL.
Molecular Mass : The recombinant human NCR3 consists of 128 amino acids after removal of the signal peptide and has a predicted molecular mass of 14.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh NCR3 is approximately 22-28 kDa due to glycosylation.
Protein Length : Met1-Gly135
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 97 % as determined by SDS-PAGE
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : NCR3 natural cytotoxicity triggering receptor 3 [ Homo sapiens ]
Official Symbol : NCR3
Synonyms : NCR3; natural cytotoxicity triggering receptor 3; LY117, lymphocyte antigen 117; 1C7; CD337; NKp30; NK-p30; lymphocyte antigen 117; activating NK-A1 receptor; activating natural killer receptor p30; natural killer cell p30-related protein; MALS; LY117;
Gene ID : 259197
mRNA Refseq : NM_001145466
Protein Refseq : NP_001138938
MIM : 611550
UniProt ID : O14931

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can NCR3 be used for personalized medicine? 08/21/2022

The study of NCR3 expression and genetic variations may help tailor treatments for individuals with certain diseases, making it a potential component of personalized medicine.

How is NCR3 protein linked to inflammatory bowel disease (IBD)? 10/11/2021

NCR3 is implicated in the pathogenesis of IBD, and drugs targeting this protein may offer new therapeutic options for patients with IBD.

How does NCR3 relate to autoimmune diseases? 09/10/2020

NCR3 dysfunction has been associated with autoimmune diseases, and understanding its role may lead to new therapies.

Are there any challenges associated with NCR3-based therapies? 06/02/2019

Challenges include potential side effects, limited understanding of NCR3 in some diseases, and the need for further clinical validation.

Are there any clinical trials involving NCR3 protein? 08/31/2018

Yes, clinical trials are exploring NCR3-based immunotherapies for various cancers and infectious diseases.

Customer Reviews (3)

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02/01/2022

    Choosing the NCR3 protein from this manufacturer not only provides me with a superior product but also grants me access to unparalleled technical support.

    12/16/2020

      The manufacturer's commitment to customer satisfaction is unmatched.

      01/13/2016

        The manufacturer's commitment to customer satisfaction and their willingness to customize solutions based on specific experimental requirements is commendable.

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