Recombinant Human PLAU protein, His-tagged
Cat.No. : | PLAU-314H |
Product Overview : | Recombinant Human PLAU (Ser21-Leu431) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | Urokinase - type plasminogen activator is also known as PLAU and UPA, a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys – Pro – Gly - Arg560 - Val561 – Val – Gly – Gly – Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction). |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ser21 |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Sodium Acetate, 100 mM NaCl, pH5.0, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 45.0 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Ser21-Leu431 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >92% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PLAU |
Official Symbol : | PLAU |
Synonyms : | PLAU; plasminogen activator, urokinase; urokinase-type plasminogen activator; UPA; URK; U-plasminogen activator; plasminogen activator, urinary; ATF; QPD; u-PA; BDPLT5 |
Gene ID : | 5328 |
mRNA Refseq : | NM_001145031 |
Protein Refseq : | NP_001138503 |
MIM : | 191840 |
UniProt ID : | P00749 |
Products Types
◆ Recombinant Protein | ||
PLAU-1697H | Recombinant Human PLAU Protein, His (Fc)-Avi-tagged | +Inquiry |
PLAU-6811M | Recombinant Mouse PLAU Protein, His (Fc)-Avi-tagged | +Inquiry |
Plau-4908M | Recombinant Mouse Plau Protein, Myc/DDK-tagged | +Inquiry |
PLAU-391C | Recombinant Cattle PLAU Protein, His-tagged | +Inquiry |
PLAU-806H | Recombinant Human PLAU Protein | +Inquiry |
◆ Native Protein | ||
PLAU-31777TH | Native Human Human SERPINE1 | +Inquiry |
PLAU-31689TH | Active Native Human Urokinase protein | +Inquiry |
PLAU -15H | Native Human HMW urokinase, HRP conjugate | +Inquiry |
◆ Lysates | ||
PLAU-1734HCL | Recombinant Human PLAU cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0703 | PLAU (Human) Chromogenic Activity Assay Kit (Indirect Assay) | +Inquiry |
Kit-0702 | PLAU (Human) Chromogenic Activity Assay Kit (Direct Assay) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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