"Cxcl5" Related Products

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Recombinant Murine Chemokine (C-X-C Motif) Ligand 5, 93aa

Cat. No.: Cxcl5-98M
Product Overview: Recombinant murine LIX is a 9.8 kDa protein consisting of 93 amino acid residues. It is produced inE.coli.
Description: The murine homolog of ENA-78 is called LIX. ENA-78/LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78/LIX is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78/LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the "ELR" motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.
Source: E.coli.
Purity: > 98% by SDS-PAGE and HPLC.
Endotoxin Level: < 0.1 ng per μg of LIX.
Stabilizer: None.
Formulation: Lyophilized.
Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml.
Reconstitution: The murine LIX should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted murine LIX should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Gene Name: Cxcl5 chemokine (C-X-C motif) ligand 5 [ Mus musculus ]
Synonyms: Cxcl5; chemokine (C-X-C motif) ligand 5; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II; granulocyte chemotactic protein-2; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B, member 15
Gene ID: 20311
mRNA Refseq: NM_009141
Protein Refseq: NP_033167
UniProt ID: P50228
Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Function: chemokine activity; cytokine activity

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