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Active Recombinant Rat Pggt1b, GST-tagged

Cat.No. : Pggt1b-325R
  • Specification
  • Gene Information
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Cat. No. : Pggt1b-325R
Description : GGTase-I (Geranylgeranyltransferase-I) catalyzes the transfer of the farnesyl and geranylgeranyl groups from farnesyl and geranylgeranyl-diphosphate to proteins ontaining a C-terminal CaaX motif, where 'C' is a conserved cysteine that is the site of farnesyl modification, 'a' is usually an aliphatic amino acid, and 'X' is leucine or phenylalanine. Farnesyltransferase (FT) and GGTase-I are closely related, sharing a common subunit and 30% identity in their β subunits. The GST-Tag facilitates the protein's application in typical GST pull-down assays.
Source : E. coli.
Form : Liquid. Supplied in 25 mM HEPES, pH 7.2, 25 mM NaCl and 5 mM DTT.
Purity : > 90% by SDS-PAGE.
Activity : 1 pmol of GGTase-I will transfer 5 pmol of Farnesyl to RhoA in 15 min at 37°C.
Usage : For in vitro use only.
Storage : Quality guaranteed for 12 months store at - 80°C. Avoid freeze / thaw cycles.
Gene Name : Pggt1b protein geranylgeranyltransferase type I, beta subunit [ Rattus norvegicus ]
Synonyms : Pggt1b; protein geranylgeranyltransferase type I, beta subunit; geranylgeranyltransferase type 1 beta; geranylgeranyltransferase type I (GGTase-I)
Gene ID : 81746
mRNA Refseq : NM_031082
Protein Refseq : NP_112344
UniProt ID : P53610
Chromosome Location : q11
Function : CAAX-protein geranylgeranyltransferase activity; drug binding; isoprenoid binding; metal ion binding; peptide binding; prenyltransferase activity; protein binding; transferase activity; zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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