"PTPRM" Related Products

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Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, M

Cat. No. : PTPRM-336H
Description : Protein Tyrosin Phosphatase, cytoplasmic region, containing catalytic domain D1 C-terminally linked to the non-catalytic domain D2. PTPmu is an Ig superfamily receptor protein-tyrosine phosphatase which promotes cell-cell adhesion in a homophilic, Ca2+independent manner and interacts with the cadherin-catenin complex. The intracellular region of PTPμ contains three domains: the juxtamembrane (JM, aa 765-923) and two phosphatase domains (D1 and D2). Only the D1 domain is catalitically active.
Source : E. coli.
Usage : For in vitro use only.
Form : Liquid. Supplied in 10 mM Tris- HCl, 10 mM Bis-Tris-HCl pH 7.0.
Activity : 1 nmol of PTPμ will hydrolyze 1.2 nmol of pNPP per minute at 37℃ at pH 4.8.
Purity : > 95% by SDS-PAGE.
Storage : Quality guaranteed for 12 months, store at -80℃. Avoid freeze / thaw cycles.
Gene Name : PTPRM protein tyrosine phosphatase, receptor type, M [ Homo sapiens ]
Synonyms : PTPRM; protein tyrosine phosphatase, receptor type, M; RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU; MGC166994; protein tyrosine phosphatase mu; protein tyrosine phosphatase, receptor type, mu polypeptide; EC 3.1.3.48
Gene ID : 5797
mRNA Refseq : NM_001105244
Protein Refseq : NP_001098714
MIM : 176888
UniProt ID : P28827
Chromosome Location : 18p11.2
Pathway : Adherens junction; Cell adhesion molecules (CAMs)
Function : cadherin binding; hydrolase activity; protein binding; receptor activity; transmembrane receptor protein tyrosine phosphatase activity

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