"RAP1B" Related Products

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Recombinant Human RAP1B, Member Of RAS Oncogene Family

Cat. No.: RAP1B-1127H
Description: Rap (Ras-proximate) proteins are GTPases that belong to the Ras superfamily of small GTP binding proteins. Rap1B is known to antagonize the mitotic and transforming activity of Ras. Rap1B can be activated by cAMP known to either stimulate or inhibit cell proliferation. The deletion of 17 C-terminal amino acids in Rap1B △C leads to the loss of the phosphorylation site Ser179 and the geranyl-geranylation site. Protein preparation is 53% GDP- and 47% GTP-loaded, measured by HPLC.MW = 19.0 kDa.
Source: E. coli.
Purity: > 95% by SDS-PAGE.
Form: Liquid. Supplied in 64 mM Tris-HCl pH 7.0, 5 mM DTE, 400 mM NaCl, 10 mM MgCl2 and 0.1 mM GDP.
Storage: Quality guaranteed for 12 months. Store at -80°C.Avoid freeze / thaw cycles.
Usage: For in vitro use only.
Gene Name: RAP1B RAP1B, member of RAS oncogene family [ Homo sapiens ]
Synonyms: RAP1B, member of RAS oncogene family; K-REV; RAL1B; DKFZp586H0723; RAP1B; RAS-related protein RAP1B; small GTP binding protein; Ras family small GTP binding protein RAP1B; OTTHUMP00000165026; GTP-binding protein smg p21B
Gene ID: 5908
mRNA Refseq: NM_001010942
Protein Refseq: NP_001010942
MIM: 179530
UniProt ID: P61224
Chromosome Location: 12q14
Pathway: Chemokine signaling pathway; Focal adhesion; Leukocyte transendothelial migration; Long-term potentiation; MAPK signaling pathway; Neurotrophin signaling pathway; Renal cell carcinoma; Diabetes pathways; Hemostasis; Integrin cell surface interactions
Function: GTP binding; GTPase activity; nucleotide binding; protein binding

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