"VPS28" Related Products

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Recombinant Human Vacuolar Protein Sorting 28 Homolog (S. cerevisiae)

Cat. No.: VPS28-1407H
Product Overview: Recombinant human VPS28 was expressed inE.coliand purified by using conventional chromatography. MW = 25.4 kDa (221aa).
Description: VPS28 is involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. This protein is a subunit of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. VSP28binding with the TSG101 may play important roles in budding of Retroviruses, such as HIV-1 and Ebola virus.
Source: E.coli.
Amino Acid Sequence: MFHGIPATPG IGAPGNKPEL YEEVKLYKNA REREKYDNMA ELFAVVKTMQ ALEKAYIKDC VSPSEYTAAC SRLLVQYKAA FRQVQGSEIS SIDEFCRKFR LDCPLAMERI KEDRPITIKD DKGNLNRCIA DVVSLFITVM DKLRLEIRAM DEIQPDLREL METMHRMSHL PPDFEGRQTV SQWLQTLSGM SASDELDDSQ VRQMLFDLES AYNAFNRFLH A
Form: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT, 10% Glycerol
Purity: > 95% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) [ Homo sapiens ]
Synonyms: VPS28; vacuolar protein sorting 28 homolog (S. cerevisiae); MGC60323;yeast class E protein Vps28p homolog; vacuolar protein sorting 28 (yeast); H-Vps28; ESCRT-I complex subunit VPS28; vacuolar protein sorting 28; Vacuolar protein sorting-associated protein 28 homolog
Gene ID: 51160
mRNA Refseq: NM_016208
Protein Refseq: NP_057292
MIM: 611952
UniProt ID: Q9UK41
Chromosome Location: 8q24.3
Pathway: Endocytosis
Function: protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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