|Cat. No. :
|Product Overview :
||Recombinant Mouse Interferon beta produced inE.Coliis a single, non-glycosylated polypeptide chain containing 162 amino acids and having a molecular mass of 19.8 kDa. Mouse IFN beta is purified by proprietary chromatographic techniques.
||Interferon-beta 1b has antiviral, antibacterial and anticancer activities. Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein. Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.
|Amino Acid Sequence :
||MINYKQLQLQERTNIRKCQELLEQLNGKINLTYRADFKIPMEMTEKMQKSYTAFAIQEMLQN VFLVFRNNFSS TGWNETIVVRLLDELHQQTVFLKTVLE EKQEERLT WEMSSTAL HLKSYYWRVQRYLKLMKYNSYAWMVVRAEIFR NFLIIRRLTRNFQN.
||Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
||IFN-b Mouse solution containing 10mM sodium phosphate pH-7.5 and 0.5M ammonium sulfate.
|Biological Activity :
||Determined in a viral cytopathic effect inhibition assay.
||Store the IFN-beta at 4°C for 4 weeks. Do not freeze/thaw.