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Recombinant Human IRAK4, GST-tagged, Active
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| Cat. No. : | IRAK4-333H |
| Product Overview : | Recombinant full-length human IRAK4 was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 81 kDa. |
| Description : | Interleukin-1 receptor-associated kinase 4 (IRAK4) is an important mediator in the signal transduction of Toll-like receptor (TLR) and IL1R family members. IRAK4 is involved in the Toll-like receptor signaling pathway leading to Apoptosis. IRAK4 has molecular functions like protein binding, ATP binding, kinase activity and magnesium ion binding. Toll/IL-1 receptor family members like IRAK4 are central components of host defense mechanisms in a variety of species. One well conserved element in their signal transduction is the Ser/Thr kinase activity which couple early signaling events in a receptor complex at the plasma membrane to larger signalosomes in the cytosol. |
| Source : | Sf9 insect cells using baculovirus. |
| Sequence : | Full-length. |
| Applications : | Kinase Assay, Western Blot. |
| Storage And Stability : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Gene Name : | IRAK4 interleukin-1 receptor-associated kinase 4 [ Homo sapiens ] |
| Synonyms : | IRAK4; interleukin-1 receptor-associated kinase 4; IPD1; REN64; NY-REN-64; EC 2.7.11.1; IRAK-4; NY-REN-64 antigen |
| Gene ID : | 51135 |
| mRNA Refseq : | NM_001114182 |
| Protein Refseq : | NP_001107654 |
| MIM : | 606883 |
| UniProt ID : | Q9NWZ3 |
| Chromosome Location : | 12q12 |
| Pathway : | Apoptosis; Neurotrophin signaling pathway; Toll-like receptor signaling pathway |
| Function : | ATP binding; interleukin-1 receptor binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity |
◆ Recombinant Protein
| IRAK4-5049H | Recombinant Human IRAK4 Protein, GST-tagged | +Inquiry |
| IRAK4-2438H | Recombinant Human IRAK4 Protein, MYC/DDK-tagged | +Inquiry |
| IRAK4-5437H | Recombinant Human Interleukin-1 Receptor-Associated Kinase 4, His-tagged | +Inquiry |
| IRAK4-976H | Recombinant Human IRAK4, His & GST tagged | +Inquiry |
| IRAK4-7074H | Recombinant Human IRAK4 protein, His-tagged | +Inquiry |
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◆ Lysates
| IRAK4-615HCL | Recombinant Human IRAK4 cell lysate | +Inquiry |
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