Recombinant Human Insulin Receptor-related Receptor, GST-tagged, Active
Cat.No. : | INSRR-334H |
Product Overview : | Recombinant human IRR (945-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 65 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | INSRR-334H |
Description : | IRR or insulin receptor-related receptor is a tyrosine protein kinase that is required for the appearance of male gonads and thus for male sexual differentiation. The expression of IRR mRNA is restricted to a few tissue types and has been detected in neuronal tissues as well as in neuroblastomas. As a result of its occurrence in neuroblastomas, it has speculated that IRR may be involved in tumor genesis. RT-PCR and solution hybridization/RNAse protection assay have shown strong coupling of IRR mRNA in 18 tumor cell lines. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | 945-end. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | INSRR insulin receptor-related receptor [ Homo sapiens ] |
Synonyms : | INSRR; insulin receptor-related receptor; IRR; IR-related receptor; EC 2.7.10.1; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; OTTHUMP00000038715 |
Gene ID : | 3645 |
mRNA Refseq : | NM_014215 |
Protein Refseq : | NP_055030 |
MIM : | 147671 |
UniProt ID : | P14616 |
Chromosome Location : | 1q21-q23 |
Pathway : | Prostate cancer; Regulation of actin cytoskeleton |
Function : | ATP binding; manganese ion binding; metal ion binding; nucleotide binding; protein binding; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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