|Cat. No. :
|Product Overview :
||Recombinant human IRR (945-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 65 kDa.
||IRR or insulin receptor-related receptor is a tyrosine protein kinase that is required for the appearance of male gonads and thus for male sexual differentiation. The expression of IRR mRNA is restricted to a few tissue types and has been detected in neuronal tissues as well as in neuroblastomas. As a result of its occurrence in neuroblastomas, it has speculated that IRR may be involved in tumor genesis. RT-PCR and solution hybridization/RNAse protection assay have shown strong coupling of IRR mRNA in 18 tumor cell lines.
||Sf9 insect cells using baculovirus.
||Kinase Assay, Western Blot.
|Storage And Stability :
||Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.