"AARS" Related Products


Recombinant Human AARS, His-tagged

Cat.No.: AARS-26881TH
Product Overview: Human Recombinant Full length AlaRS produced in SF9 cells with a 6xHis tag, 107,598 Dalton.
Description: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes.Class II tRNA synthases evolved early in evolution and are highly conserved.This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein.tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons.They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Conjugation: HIS
Biological activity: AARS-26881TH is reactive against Polymyositis sera.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 250mM Sodium chloride, 16mM HEPES, pH 8
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Gene Name: AARS alanyl-tRNA synthetase [ Homo sapiens ]
Official Symbol: AARS
Synonyms: AARS; alanyl-tRNA synthetase; alanyl-tRNA synthetase, cytoplasmic; alanine tRNA ligase 1; cytoplasmic;
Gene ID: 16
mRNA Refseq: NM_001605
Protein Refseq: NP_001596
MIM: 601065
Uniprot ID: P49588
Chromosome Location: 16q22
Pathway: Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Cytosolic tRNA aminoacylation, organism-specific biosystem;
Function: ATP binding; alanine-tRNA ligase activity; amino acid binding; aminoacyl-tRNA editing activity; ligase activity;

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