"Cxcl10" Related Products

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Recombinant Rat Chemokine (C-X-C motif) Ligand 10

Cat. No.: Cxcl10-121R
Product Overview: Recombinant rat IP-10 produced inE.coliis an 8.6 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.
Description: IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectivelychemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells.
Source: E.coli.
Purity: Greater than 98% (determined by SDS-PAGE and HPLC analysis).
Endotoxin Level: < 0.1 ng per μg of rRa IP-10 (1EU/μg).
Biological Activity: Determined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10.0-50.0 ng/ml.
Formulation: Lyophilized from a sterile-filtered solution with no additives.
Reconstitution: Please Note: Always centrifuge product before opening vial. The lyophilized protein should be reconstituted with distilled, sterile water to a concentration of 0.1-1.0 mg/ml. For further dilution, carrier protein (0.1% BSA or HSA) should be added to avoid loss of bioactivity.
Storage & Stability: The lyophilized powder, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted CTACK should be used immediately or stored in undiluted working aliquots at -20°C. Avoid repeated freeze / thaw cycles.
Gene Name: Cxcl10 chemokine (C-X-C motif) ligand 10 [ Mus musculus ]
Synonyms: chemokine (C-X-C motif) ligand 10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10; Cxcl10; interferon activated gene 10; small inducible cytokine B subfamily (Cys-X-Cys), member 10
Gene ID: 15945
mRNA Refseq: NM_021274
Protein Refseq: NP_067249
UniProt ID: P17515
Chromosome Location: 5 53.0 cM
Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway
Function: chemokine activity; cytokine activity

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