Recombinant Human SMAD Family Member 5, GST-tagged
Cat.No. : | SMAD5-1493H |
Product Overview : | Recombinant full-length human SMAD5 was expressed inE. colicells using an N-terminal GST tag. MW = 82 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SMAD5-1493H |
Description : | SMAD5 is a member of the SMAD family and mediates signaling by the transforming growth factor-beta (TGFβ) superfamily and related ligands. SMAD5 plays a critical role in the signaling pathway by which TGFβ inhibits the proliferation of human hematopoietic progenitor cells. SMAD5 is up-regulated in gastric epithelial cells during the infection of the pathogen Helicobacter pylori and it mediates apoptosis of gastric epithelial cells induced by H. pylori infection. In mature human B cells, bone morphogenetic protein 6 (BMP-6) inhibits cell growth and rapidly induces phosphorylation of SMADs 5 and 8. |
Source : | E. coli. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | SMAD5 SMAD family member 5 [ Homo sapiens ] |
Synonyms : | SMAD5; SMAD family member 5; Dwfc; JV5-1; MADH5; DKFZp781C1895; DKFZp781O1323; MAD homolog 5; SMA- and MAD-related protein 5; SMAD, mothers against DPP homolog 5; mothers against decapentaplegic homolog 5; MAD, mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; MAD, mothers against decapentaplegic homolog 5 (Drosophila); SMAD, mothers against DPP homolog 5 (Drosophila); Mothers against DPP homolog 5; SMAD 5; Smad5; hSmad5; mothers against decapentaplegic, drosophila, homolog of, 5 |
Gene ID : | 4090 |
mRNA Refseq : | NM_001001419 |
Protein Refseq : | NP_001001419 |
MIM : | 603110 |
UniProt ID : | Q99717 |
Chromosome Location : | 5q31 |
Pathway : | TGF-beta signaling pathway |
Function : | protein binding; receptor signaling protein activity; transcription activator activity; transcription factor activity; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity |
Products Types
◆ Recombinant Protein | ||
Smad5-3245M | Recombinant Mouse Smad5 protein(Thr2-Ser465), His&GST-tagged | +Inquiry |
SMAD5-4149R | Recombinant Rhesus Macaque SMAD5 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMAD5-303H | Recombinant Human SMAD5 Protein, His-tagged | +Inquiry |
Smad5-3220M | Recombinant Mouse Smad5 protein(Thr2-Ser465) | +Inquiry |
SMAD5-4333R | Recombinant Rhesus monkey SMAD5 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
SMAD5-001MCL | Recombinant Mouse SMAD5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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