Recombinant Human CX3CL1 CX3CL1-28060TH

Recombinant Human CX3CL1

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Recombinant Human CX3CL1

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Cat. No. : CX3CL1-28060TH
Product Overview : Recombinant human CX3CL1 is a non-glycosylated protein, containing 76 amino acids, with a molecular weight of 8.6 kDa.
Description : Fractalkine, also known as CX3CL1, is an atypical chemokine that was the first of a fourth chemokine motif (CX3C). It is thought to function as a T cell and monocyte chemotractant and is produced by non-haemopoietic cells. Fractalkine is made in a soluble and membrane bound form in activated endothelial cells which is thought to promote adhesion of leukocytes.
Source : E. coli
BiologicalActivity : The activity is determined by the dose dependent chemotaxis of human PBMCs and is typically starting between 10-100 ng/mL.
Form : Lyophilized with no additives.
Purity : >95% by SDS-PAGE
Endotoxin Level : Measured by kinetic LAL analysis and is typically < 1 EU/μg protein.
AASequence : QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG
Reconstitution : It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.
Storage : Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
OfficialSymbol : CX3CL1
Gene Name : CX3CL1 chemokine (C-X3-C motif) ligand 1 [ Homo sapiens ]
Synonyms : CX3CL1; chemokine (C-X3-C motif) ligand 1; SCYD1, small inducible cytokine subfamily D (Cys X3 Cys), member 1 (fractalkine, neurotactin); fractalkine; ABCD 3; C3Xkine; CXC3; CXC3C; neurotactin; NTN;
Gene ID : 6376
mRNA Refseq : NM_002996
Protein Refseq : NP_002987
MIM : 601880
UniProt ID : P78423
Chromosome Location : 16q13
Pathway : Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem;
Function : chemokine activity; protein binding; receptor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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