Recombinant Human CYLD
Cat.No. : | CYLD-27021TH |
Product Overview : | Recombinant fragment of Human CYLD with N terminal proprietary tag, 36.63kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Detected in fetal brain, testis, and skeletal muscle, and at a lower level in adult brain, leukocytes, liver, heart, kidney, spleen, ovary and lung. Isoform 2 is found in all tissues except kidney. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | QNMELFAVLCIETSHYVAFVKYGKD DSAWLFFDSMADRDGGQNGFNIPQV TPCPEVGEYLKMSLEDLHSLDSRRI QGCARRLLCDAYMCMYQSPTMSLYK |
Sequence Similarities : | Belongs to the peptidase C67 family.Contains 3 CAP-Gly domains. |
Gene Name : | CYLD cylindromatosis (turban tumor syndrome) [ Homo sapiens ] |
Official Symbol : | CYLD |
Synonyms : | CYLD; cylindromatosis (turban tumor syndrome); CYLD1; ubiquitin carboxyl-terminal hydrolase CYLD; KIAA0849; ubiquitin specific peptidase like 2; USPL2; |
Gene ID : | 1540 |
mRNA Refseq : | NM_015247 |
Protein Refseq : | NP_056062 |
MIM : | 605018 |
Uniprot ID : | Q9NQC7 |
Chromosome Location : | 16q12-q13 |
Pathway : | Canonical NF-kappaB pathway, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; NOD1/2 Signaling Pathway, organism-specific biosystem; Negative regulators of RIG-I/MDA5 signaling, organism-specific biosystem; |
Function : | cysteine-type peptidase activity; metal ion binding; peptidase activity; proline-rich region binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
CYLD-1371R | Recombinant Rat CYLD Protein, His (Fc)-Avi-tagged | +Inquiry |
CYLD-696H | Recombinant Human CYLD Protein, His (Fc)-Avi-tagged | +Inquiry |
CYLD-668H | Recombinant Human CYLD Protein, His-tagged | +Inquiry |
Cyld-2408M | Recombinant Mouse Cyld Protein, Myc/DDK-tagged | +Inquiry |
CYLD-23H | Active Recombinant Human CYLD Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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