Recombinant Human DDB1 protein, GST-tagged

• Cat.No.: DDB1-28308TH
• Product Overview: Recombinant Human DDB1(1 a.a. - 1140 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 153.4 kDa
• AA Sequence: MSYNYVVTAQKPTAVNGCVTGHFTS AEDLNLLIAKNTRLEIYVVTAEGLR PVKEVGMYGKIAVMELFRPKGESKD LLFILTAKYNACILEYKQSGESIDI ITRAHGNVQDRIGRPSETGIIGIID PECRMIGLRLYDGLFKVIPLDRDNK ELKAFNIRLEELHVIDVKFLYGCQA PTICFVYQDPQGRHVKTYEVSLREK EFNKGPWKQENVEAEASMVIAVPEP FGGAIIIGQESITYHNGDKYLAIAP PIIKQSTIVCHNRVDPNGSRYLLGD MEGRLFMLLLEKEEQMDGTVTLKDL RVELLGETSIAECLTYLDNGVVFVG SRLGDSQLVKLNVDSNEQGSYVVAM ETFTNLGPIVDMCVVDLERQGQGQL VTCSGAFKEGSLRIIRNGIGIHEHA SIDLPGIKGLWPLRSDPNRETDDTL VLSFVGQTRVLMLNGEEVEETELMG FVDDQQTFFCGNVAHQQLIQITSAS VRLVSQEPKALVSEWKEPQAKNISV ASCNSSQVVVAVGRALYYLQIHPQE LRQISHTEMEHEVACLDITPLGDSN GLSPLCAIGLWTDISARILKLPSFE LLHKEMLGGEIIPRSILMTTFESSH YLLCALGDGALFYFGLNIETGLLSD RKKVTLGTQPTVLRTFRSLSTTNVF ACSDRPTVIYSSNHKLVFSNVNLKE VNYMCPLNSDGYPDSLALANNSTLT IGTIDEIQKLHIRTVPLYESPRKIC YQEVSQCFGVLSSRIEVQDTSGGTT ALRPSASTQALSSSVSSSKLFSSST APHETSFGEEVEVHNLLIIDQHTFE VLHAHQFLQNEYALSLVSCKLGKDP NTYFIVGTAMVYPEEAEPKQGRIVV FQYSDGKLQTVAEKEVKGAVYSMVE FNGKLLASINSTVRLYEWTTEKELR TECNHYNNIMALYLKTKGDFILVGD LMRSVLLLAYKPMEGNFEEIARDFN PNWMSAVEILDDDNFLGAENAFNLF VCQKDSAATTDEERQHLQEVGLFHL GEFVNVFCHGSLVMQNLGETSTPTQ GSVLFGTVNGMIGLVTSLSESWYNL LLDMQNRLNKVIKSVGKIEHSFWRS FHTERKTEPATGFIDGDLIESFLDI SRPKMQEVVANLQYDDGSGMKREAT ADDLIKVVEELTRIH
• Applications: Enzyme-linked Immunoabsorbent; Assay Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: DDB1 damage-specific DNA binding protein 1, 127kDa [ Homo sapiens ]
• Official Symbol: DDB1
• Synonyms: DDB1; damage-specific DNA binding protein 1, 127kDa; damage specific DNA binding protein 1 (127kD); DNA damage-binding protein 1; XPE; XAP-1; UV-DDB 1; DDB p127 subunit; XPE-binding factor; HBV X-associated protein 1; DNA damage-binding protein a; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; damage-specific DNA-binding protein 1; xeroderma pigmentosum group E-complementing protein; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1
• Gene ID: 1642
• mRNA Refseq: NM_001923
• Protein Refseq: NP_001914
• MIM: 600045
• UniProt ID: Q16531
• Chromosome Location: 11q12-q13
• Pathway: Cul4-DDB1-CSA complex, organism-specific biosystem; Cul4-DDB1-DDB2 complex, organism-specific biosystem; DNA Repair, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Formation of incision complex in GG-NER, organism-specific biosystem; Global Genomic NER (GG-NER), organism-specific biosystem; Nucleotide Excision Repair, organism-specific biosystem
• Function: DNA binding; damaged DNA binding; protein binding