Recombinant Human DRD1, C-MYC-tagged

• Cat.No.: DRD1-28086TH
• Product Overview: Recombinant full length Human Dopamine Receptor D1 with an N terminal c-myc tag expressed in Sf9 insect cells; amino acids 1-446.

Specification

• Description: This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
• Conjugation: C-MYC
• Biological activity: Receptor expression level: 3.5pmol/mg.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: DRD1 dopamine receptor D1 [ Homo sapiens ]
• Official Symbol: DRD1
• Synonyms: DRD1; dopamine receptor D1; D(1A) dopamine receptor
• Gene ID: 1812
• mRNA Refseq: NM_000794
• Protein Refseq: NP_000785
• MIM: 126449
• Uniprot ID: P21728
• Chromosome Location: 5q34-q35
• Pathway: Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Dopamine receptors, organism-specific biosystem
• Function: G-protein coupled receptor activity; dopamine binding; dopamine receptor activity; dopamine receptor activity, coupled via Gs; dopamine receptor activity, coupled via Gs