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Recombinant Human DVL3

Cat.No. : DVL3-28353TH
Product Overview : Recombinant full length Human Dishevelled 3 with a N terminal proprietary tag: predicted molecular weight 104.83 kDa inclusive of tag.
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  • Gene Information
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Description : This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
Protein length : 716 amino acids
Molecular Weight : 104.830kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRP SYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVS AEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPH AGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNG TAKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSR FSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITD STMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGS IMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR EIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAA WVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTER LDDFHLSIHSDMAAIVKAMASPESGLEVRDRMLLKITIPN AFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHT VNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDT LAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSY GGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGG SGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSL ASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPPPAAMGPPG APPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM
Sequence Similarities : Belongs to the DSH family.Contains 1 DEP domain.Contains 1 DIX domain.Contains 1 PDZ (DHR) domain.
Gene Name : DVL3 dishevelled, dsh homolog 3 (Drosophila) [ Homo sapiens ]
Official Symbol : DVL3
Synonyms : DVL3; dishevelled, dsh homolog 3 (Drosophila); dishevelled 3 (homologous to Drosophila dsh); segment polarity protein dishevelled homolog DVL-3; KIAA0208;
Gene ID : 1857
mRNA Refseq : NM_004423
Protein Refseq : NP_004414
MIM : 601368
Uniprot ID : Q92997
Chromosome Location : 3q27
Pathway : Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; HTLV-I infection, organism-specific biosystem;
Function : beta-catenin binding; frizzled binding; protease binding; protein binding; protein heterodimerization activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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