Recombinant Human EBI3, His-tagged

• Cat.No.: EBI3-27028TH
• Product Overview: Recombinant Full length Human EBI3 with an amino-terminal hexahistidine tag; amino acids 21-229 , 24kDa.

Specification

• Description: This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 50% Glycerol, PBS, pH 7.2
• Storage: Store at -20°C. Stable for 12 months at -20°C
• Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.Contains 2 fibronectin type-III domains.

Gene Information

• Gene Name: EBI3 Epstein-Barr virus induced 3 [ Homo sapiens ]
• Official Symbol: EBI3
• Synonyms: EBI3; Epstein-Barr virus induced 3; interleukin-27 subunit beta; IL27 subunit; IL35 subunit
• Gene ID: 10148
• mRNA Refseq: NM_005755
• Protein Refseq: NP_005746
• MIM: 605816
• Uniprot ID: Q14213
• Chromosome Location: 19p13
• Pathway: IL27-mediated signaling events, organism-specific biosystem
• Function: cytokine activity; cytokine receptor activity; interleukin-27 receptor binding