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Recombinant Human EDF1, His-tagged

Cat.No. : EDF1-28461TH
Product Overview : Recombinant full length protein, corresponding to amino acids 1-148 of Human EDF1 with N terminal His tag, 25kDa.
  • Specification
  • Gene Information
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Description : This gene encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.
Conjugation : HIS
Source : E. coli
Tissue specificity : Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.
Form : Lyophilised:Reconstitute with 48 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Store at 4°C. Upon reconstitution store at -80oC.
Sequences of amino acids : MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVET SKKWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVG KVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNN QVLGKIERAIGLKLRGKDIGKPIEKGPRAK
Sequence Similarities : Contains 1 HTH cro/C1-type DNA-binding domain.
Gene Name : EDF1 endothelial differentiation-related factor 1 [ Homo sapiens ]
Official Symbol : EDF1
Synonyms : EDF1; endothelial differentiation-related factor 1; EDF 1; multiprotein bridging factor 1;
Gene ID : 8721
mRNA Refseq : NM_003792
Protein Refseq : NP_003783
MIM : 605107
Uniprot ID : O60869
Chromosome Location : 9q34.3
Function : calmodulin binding; NOT histone acetyltransferase activity; NOT methyltransferase activity; protein binding; sequence-specific DNA binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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