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Recombinant Human EHMT1, His-tagged

Cat.No. : EHMT1-27743TH
Product Overview : Recombinant fragment, corresponding to amino acids 460-716 of Human KMT1D / GLP / Eu HMTase1 with N terminal His tag; 257 amino acids, 38kDa.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 103 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : SQNCVTSPMNIDRNITHLQYCVCID DCSSSNCMCGQLSMR CWYDKDGRLLPEFNMAEPPLIFECN HACSCWRNCRNRV VQNGLRARLQLYRTRDMGWGVRSLQ DIPPGTFVCEYVGELISDSEADVRE EDSYLFDLDNKDGEVYCIDARFYGN VSR FINHHCEPNLVPVRVFMAHQDLRFP RIAFFSTRLIEAG EQLGFDYGERFWDIKGKLFSCRCGS PKCRHSSAALAQRQA SAAQEAQEDGLPDTSSAAAADPL
Gene Name : EHMT1 euchromatic histone-lysine N-methyltransferase 1 [ Homo sapiens ]
Official Symbol : EHMT1
Synonyms : EHMT1; euchromatic histone-lysine N-methyltransferase 1; euchromatic histone methyltransferase 1; histone-lysine N-methyltransferase EHMT1; bA188C12.1; Eu HMTase1; FLJ12879; KIAA1876; KMT1D;
Gene ID : 79813
mRNA Refseq : NM_024757
Protein Refseq : NP_079033
MIM : 607001
Uniprot ID : Q9H9B1
Chromosome Location : 9
Pathway : Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem;
Function : histone methyltransferase activity (H3-K27 specific); histone methyltransferase activity (H3-K9 specific); histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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