Recombinant Human EIF3D, His-tagged
Cat.No. : | EIF3D-26387TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 148-330 of Human EIF3D with an N terminal His tag; Predicted MWt 22 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitute with 84 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | QKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEV SEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFH TVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVY SWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQD EGNSFNSPRNLAMEATYINHNFSQQCLRM |
Sequence Similarities : | Belongs to the eIF-3 subunit D family. |
Gene Name : | EIF3D eukaryotic translation initiation factor 3, subunit D [ Homo sapiens ] |
Official Symbol : | EIF3D |
Synonyms : | EIF3D; eukaryotic translation initiation factor 3, subunit D; EIF3S7, eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; eukaryotic translation initiation factor 3 subunit D; eIF3 p66; eIF3 zeta; eIF3d; |
Gene ID : | 8664 |
mRNA Refseq : | NM_003753 |
Protein Refseq : | NP_003744 |
MIM : | 603915 |
Uniprot ID : | O15371 |
Chromosome Location : | 22q13.1 |
Pathway : | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of a pool of free 40S subunits, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; |
Function : | protein binding; contributes_to translation initiation factor activity; contributes_to translation initiation factor activity; |
Products Types
◆ Recombinant Protein | ||
EIF3D-3178H | Recombinant Human EIF3D Protein, GST-tagged | +Inquiry |
EIF3D-2711M | Recombinant Mouse EIF3D Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF3D-326H | Recombinant Human EIF3D Protein, MYC/DDK-tagged | +Inquiry |
EIF3D-822H | Recombinant Human EIF3D Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF3D-1715R | Recombinant Rat EIF3D Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
EIF3D-6663HCL | Recombinant Human EIF3D 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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