Recombinant Human EPHX1

• Cat.No.: EPHX1-28685TH
• Product Overview: Recombinant full length Human Epoxide hydrolase with N terminal proprietary tag, predicted mwt: 76.12 kDa.

Specification

• Description: Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Protein length: 455 amino acids
• Molecular Weight: 76.120kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Found in liver.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRS AAREDDSIRPFKVETSDEEIHDLHQRIDKFRFTPPLEDSC FHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKI EGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKI IPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSKKGFN SVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVP SHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTERDVE LLYPVKEKVFYSLMRESGYMHIQCTKPDTVGSALNDSPVG LAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVML YWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSA FPFELLHTPEKWVRFKYPKLISYSYMVRGGHFAAFEEPEL LAQDIRKFLSVLERQ
• Sequence Similarities: Belongs to the peptidase S33 family.

Gene Information

• Gene Name: EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) [ Homo sapiens ]
• Official Symbol: EPHX1
• Synonyms: EPHX1; epoxide hydrolase 1, microsomal (xenobiotic); EPHX; epoxide hydrolase 1
• Gene ID: 2052
• mRNA Refseq: NM_000120
• Protein Refseq: NP_000111
• Uniprot ID: P07099
• Chromosome Location: 1q42.1
• Pathway: Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem
• Function: cis-stilbene-oxide hydrolase activity; epoxide hydrolase activity; hydrolase activity