Recombinant Human ERCC3
Cat.No. : | ERCC3-30702TH |
Product Overview : | Recombinant full length Human XPB with a N terminal proprietary tag; predicted MW: 112.09 kDa inclusive of tag. P19447, |
- Specification
- Gene Information
- Related Products
Description : | ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription. |
Protein length : | 782 amino acids |
Molecular Weight : | 112.090kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPS AAGKQVDESGTKVDEYGAKDYRLQMPLKDDHTSRPLWVAP DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTA YSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCT VSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLR NSEGEATELITETFTSKSAISKTAESSGGPSTSRVTDPQG KSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEEL QKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKR CLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKP IGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDL NFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYR EYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNP KINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRL GRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL VDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKVLAAT DLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYME YHSSRSKAPSKHVHPLFKRFRK |
Sequence Similarities : | Belongs to the helicase family. RAD25/XPB subfamily.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain. |
Gene Name : | ERCC3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) [ Homo sapiens ] |
Official Symbol : | ERCC3 |
Synonyms : | ERCC3; excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing); TFIIH basal transcription factor complex helicase XPB subunit; BTF2; GTF2H; RAD25; TFIIH; XPB; |
Gene ID : | 2071 |
mRNA Refseq : | NM_000122 |
Protein Refseq : | NP_000113 |
MIM : | 133510 |
Uniprot ID : | P19447 |
Chromosome Location : | 2q21 |
Pathway : | Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; DNA Repair, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; |
Function : | 3-5 DNA helicase activity; 3-5 DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; ATPase activity; |
Products Types
◆ Recombinant Protein | ||
ERCC3-2843M | Recombinant Mouse ERCC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERCC3-3459H | Recombinant Human ERCC3 Protein, GST-tagged | +Inquiry |
ERCC3-1316R | Recombinant Rhesus Macaque ERCC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERCC3-1794R | Recombinant Rat ERCC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERCC3-239C | Recombinant Cynomolgus Monkey ERCC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ERCC3-6565HCL | Recombinant Human ERCC3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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