Recombinant Human ETHE1, His-tagged

• Cat.No.: ETHE1-28406TH
• Product Overview: Recombinant fragment, corresponding to amino acids 23-239 of Human ETHE1 with an N terminal His tag. Observed mwt: 25 kDa

Specification

• Description: This gene encodes a sulfur dioxygenase that localizes within the mitochondrial matrix. The enzyme functions in sulfide catabolism. Mutations in this gene result in ethylmalonic encephalopathy.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Ubiquitously expressed.
• Form: Lyophilised:Reconstitute with 117 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: ILLRQMFEPVSCTFTYLLGDRESRE AVLIDPVLETAPRDA QLIKELGLRLLYAVNTHCHADHITG SGLLRSLLPGCQS VISRLSGAQADLHIEDGDSIRFGRF ALETRASPGHTPGCVTFVLNDHSMA FTGDALLIRGCGRTDFQQGCAKTLY HSV HEKIFTLPGDCLIYPAHDYHGFTVS TVEEERTLNPRLT LSCEEFVKIMGNLNLPKPQQIDF
• Sequence Similarities: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

Gene Information

• Gene Name: ETHE1 ethylmalonic encephalopathy 1 [ Homo sapiens ]
• Official Symbol: ETHE1
• Synonyms: ETHE1; ethylmalonic encephalopathy 1; protein ETHE1, mitochondrial; HSCO; YF13H12
• Gene ID: 23474
• mRNA Refseq: NM_014297
• Protein Refseq: NP_055112
• MIM: 608451
• Uniprot ID: O95571
• Chromosome Location: 19q13.32
• Function: hydrolase activity; metal ion binding