| Description : |
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
| Conjugation : |
HIS |
| Source : |
E. coli |
| Form : |
Lyophilised:Reconstitute with 104 μl aqua dest. |
| Storage buffer : |
Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
| Storage : |
Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
GRKYQSKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKT LENFFASADEELTIDHVPIWCKNSQGQRVMVEQSEKLN GVLEASRLWDNMRKLGECTEEAHQMTHDGYLKLWQLSKPS LASFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQ QIYTFRGAVNALFTVPHTHVFYLTQSFRFGVEIAYVGA TILDVCKRVRKKTLVGGNHQSGIRGDAKGQVALLSRTNAN VFDEAVRVTEGEFPSRIHLIGGIKSFGLDRIIDIWILL QPEEERRKQNLVIKDKFIRRWVHKEGFSGFKRYVTAAE DKELEAKIAVVEKYNIRIPELVQRIEKCHIEDLDFAEYIL GTVHKAKGLEFDTVHVLDDFVKVPCARHNLPQLPHFRV ESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGEY FLQAELTSNVLKTGVVRCCVGQCNNAIPVDTVLTMKKLPI TYSNRKENKGGYLCHSCAEQRIGPLAFLTASPEQVRAM ERTVENIVLPRHEALLFLVF |
